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Filtered Search Results
eMolecules EMOLECULES INC
5000470874 BENZYL PROPIOLATE 5G
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.9% | 50 MG
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Cediranib maleate is a highly potent, orally available VEGFR inhibitor. It effectively inhibits VEGF-stimulated proliferation and KDR phosphorylation in human umbilical vein endothelial cells and reduces vessel sprouting in coculture models. In vivo, it ablates experimental angiogenesis and inhibits the growth of various human tumor xenografts.
- Highly potent, orally available VEGFR inhibitor
- Inhibits VEGF-stimulated proliferation and KDR phosphorylation
- Reduces vessel area, length, and branching at subnanomolar concentrations
- Ablates experimental angiogenesis
- Inhibits growth of established human tumor xenografts
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Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 | C18H24N2O4 | 1 MG
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Cipralisant maleate is a research-grade histamine H3 receptor ligand used in pharmacology and neuroscience research. It acts as a potent, selective H3 receptor antagonist in vivo and may display agonist activity in certain in vitro assays. The material is supplied as a high-purity solid and is intended for experimental use under appropriate laboratory conditions.
- Potent, selective histamine H3 receptor ligand.
- Suitable for in vitro and in vivo pharmacology studies.
- High reported purity (≈99.8%).
- Stable as a powder when stored under recommended cold conditions.
- Available in small package sizes for research, including 1 mg.
- White to off-white solid appearance.
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Selleck Chemical LLC Dimethindene maleate-E1796-1G
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Dimethindene maleate is a selective antagonist of histamine H1 and exhibits antihistamine effects It suppresses the cromakalim-induced/glibenclamide-sensitive K currents in a concentration-dependent and reversible manner
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eMolecules 922-67-8 | Methyl propiolate | Ochem Incorporation | MFCD00008572 | 84.074 | C4H4O2 | 95.000 | COC(=O)C#C | 50g | 773165771
Methyl propiolate | Ochem Incorporation | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 95.000 | COC(=O)C#C | 50g | 773165771
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Medchemexpress LLC Monostearyl maleate | 2424-62-6 | MFCD08274815 | 98.0% | 368.55 g/mol | C22H40O4 | 5 G
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Monostearyl maleate (octadecyl fumarate) is a long-chain alkyl ester used as a research-grade chemical intermediate and reagent. It is typically employed in formulation development, material science, and synthetic chemistry where hydrophobic fumarate esters are required. Reported purity is 98.0% and molecular weight is 368.55 g/mol.
- High purity (98.0%) suitable for research use.
- Long hydrophobic alkyl chain for improved lipid compatibility.
- Useful as a synthetic intermediate in esterification and polymer studies.
- Supplied in multiple package sizes to support small-scale research.
- Characterized with CAS number for unambiguous identification.
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Selleck Chemical LLC Edonerpic maleate
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Edonerpic maleate (T-817) is a novel neurotrophic agent which can inhibit amyloid- peptides (A )
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 10mM (in 1mL DMSO)
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NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Medchemexpress LLC Setiptiline maleate | 85650-57-3 | 99.9% | 377.43 | 1 ML
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Setiptiline maleate is a tetracyclic antidepressant (TeCA) that functions as a noradrenergic and specific serotonergic antidepressant (NaSSA). It acts as a norepinephrine reuptake inhibitor and an α2-adrenergic receptor antagonist, as well as a serotonin receptor antagonist, likely affecting the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes. It also functions as an H1 receptor inverse agonist/antihistamine, making it suitable for research applications.
- High purity (99.94%) for reliable research
- Well-characterized pharmacological actions
- Inhibits norepinephrine reuptake
- Antagonizes α2-adrenergic receptors
- Antagonizes serotonin receptors (5-HT2A, 5-HT2C, and/or 5-HT3)
- Acts as an H1 receptor inverse agonist/antihistamine
- Detailed solubility information and protocols for in vitro and in vivo studies
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Apexbio Technology LLC Paroxetine maleate 64006-44-6 50mg
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Paroxetine maleate (CAS 64006-44-6) is a selective serotonin reuptake inhibitor (SSRI) that blocks the reabsorption of serotonin into presynaptic neurons resulting in elevated synaptic serotonin levels and modulation of neurotransmission This compound is widely utilized in the investigation of serotonergic signaling related to anxiety disorders including generalized anxiety disorder post-traumatic stress disorder and premenstrual dysphoric disorder Additionally paroxetine maleate serves as a research tool in studies probing the neuropharmacological mechanisms of chronic headache and its prospective therapeutic interventions
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Medchemexpress LLC WAY-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g·mol⁻¹ | C29H38N4O6 | 50 MG
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WAY-100635 maleate is the maleate salt of WAY-100635, a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist used in pharmacological research. It is supplied as a high-purity solid for use in receptor binding and functional assays.
- Potent 5-HT1A antagonist with IC50 ~0.91 nM and Ki ~0.39 nM.
- High purity, typically ≥99.5% by supplier analysis.
- White to off-white solid suitable for formulation and assay work.
- High solubility in DMSO; aqueous solutions may require sonication or warming.
- Stable when sealed and stored cold; long-term solvent storage at -80°C is recommended.
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Apexbio Technology LLC L-693,403 maleate 207455-21-8 50mg
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L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms
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Selleck Chemical LLC Pyrilamine Maleate S4382-25mg
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Pyrilamine Maleate (Mepyramine)is a histamine H1 receptor inverse agonist it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling
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Medchemexpress LLC PD-168077 maleate | 630117-19-0 | 99.6% | 450.49 | 50 MG
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PD-168077 maleate is a selective dopamine D4 receptor agonist with a Ki of 9 nM. It exhibits high selectivity over other D2-like and D1-like receptor family members, as well as α1, α2, 5-HT1A, and 5-HT2A receptors. This compound shows intrinsic activity at the D4 receptor, inhibiting forskolin-stimulated cAMP accumulation or stimulating [3H]thymidine uptake in CHO cells expressing the human D4 receptor. In vivo, PD-168077 dose-dependently induces locomotion.
- Selective dopamine D4 receptor agonist
- Exhibits high selectivity over other D2-like, D1-like, α1, α2, 5-HT1A, and 5-HT2A receptors
- Shows intrinsic activity at the D4 receptor
- Induces locomotion in vivo
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Medchemexpress LLC 1-Octadecyl (2Z)-2-butenedioate | 2424-62-6 | MFCD08274815 | ≥98.0% | 368.55 g/mol | C22H40O4 | 500 MG
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Monostearyl maleate (1-Octadecyl (2Z)-2-butenedioate) is a long-chain alkyl ester used as a specialty reagent and intermediate in chemical synthesis and formulation research. It is supplied as a white to off-white solid and characterized for analytical and preparative work.
- High purity: ≥98.0%.
- Molecular formula: C22H40O4.
- Molecular weight: 368.55 g/mol.
- Appearance: white to off-white solid.
- Storage: store at room temperature; in solvent, -80°C (2 years) or -20°C (1 year).
- Analytical data: 1H NMR consistent with structure.
- Typical uses: ester intermediate and formulation reagent for research applications.
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